Service and Product Launches in 2020 Q3
2020年09月30日
- Uptake Transporter Assays THTR1-HEK293 and THTR2-HEK293 with thiamine
The THTR1 and THTR2 transporter were made newly available in our portfolio!
- P-gp are now available: PSC-833 (valspodar), verapamil and ketoconazole
- BCRP are now available: Ko143, novobiocin, FTC
Additional P-gp inhibitors were characterized for P-gp (MDR1) and BCRP in Caco-2 and newly added to our portfolio!
- Caco-2 Monolayer Assay Caco-2 with sulfasalazine
Our Caco-2 assay has in addition to Estrone-3-sulfate now also been characterized with sulfasalazine as BCRP probe substrate!
- Uptake Transporter Assays BCRP-HEK293 with rosuvastatin
The BCRP assay was fully characterized with a clinically relevant substrate.
- Uptake Transporter Assays dogSglt2 (dSglt2)-HEK293 with methyl-α-D-glucopyranoside (AMG)
The dogSglt2 transporter was made newly available in our portfolio!
- Uptake Transporter Assays mouseSglt2 (mSglt2)-HEK293 with methyl-α-D-glucopyranoside (AMG)
The mouseSglt2 transporter was made newly available in our portfolio!
- Uptake Transporter Assays SGLT6-HEK293 with myo-inositol (MI)
The SGLT6 transporter was made newly available in our portfolio!
- MDCKII Monolayer Assays Abcb1KO-MDCKII-MDR1 with digoxin
Human MDR1 was expressed into canine-P-gp knock-out MDCKII cells transfected and the cell line added newly to our portfolio!
- Uptake Transporter Assays SGLT5-HEK293 with D-fructose
The SGLT5 transporter was made newly available in our portfolio!
- Uptake Transporter Assays OAT4-HEK293 with estrone-3-sulfate
- Uptake Transporter Assays OAT1-HEK293 and OAT3-HEK293 with uric acid
In addition to using uric acid as substrate for OAT4, the assay was characterized with E3S as well! Uric acid was fully characterized as new substrate in our existing for OAT1 and OAT3 cell lines!
