2020年09月30日
The THTR1 and THTR2 transporter were made newly available in our portfolio!
Additional P-gp inhibitors were characterized for P-gp (MDR1) and BCRP in Caco-2 and newly added to our portfolio!
Our Caco-2 assay has in addition to Estrone-3-sulfate now also been characterized with sulfasalazine as BCRP probe substrate!
The BCRP assay was fully characterized with a clinically relevant substrate.
The dogSglt2 transporter was made newly available in our portfolio!
The mouseSglt2 transporter was made newly available in our portfolio!
The SGLT6 transporter was made newly available in our portfolio!
Human MDR1 was expressed into canine-P-gp knock-out MDCKII cells transfected and the cell line added newly to our portfolio!
The SGLT5 transporter was made newly available in our portfolio!
In addition to using uric acid as substrate for OAT4, the assay was characterized with E3S as well! Uric acid was fully characterized as new substrate in our existing for OAT1 and OAT3 cell lines!